(+/-)-Verapamil hydrochloride [152-11-4] |
This product is calcium antagonists, can be selective expansion of coronary artery, increasing coronary blood flow; can inhibit cardiac excitability and atrioventricular conduction. For the treatment of paroxysmal supraventricular tachycardia. |
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Aliskiren [173334-57-1] |
Is a new molecular entities, directly inhibit the enzyme renin renal hypertension caused by high blood pressure therapies. |
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2-Fluoroadenosine [146-78-1] |
Fludarabine intermediate |
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6-Thioxanthine [2002-59-7] |
used for antineoplastic agent; Azathioprine intermediate; |
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Altretamine [645-05-6] |
This product is pyrimidine antimetabolites, mainly inhibit dihydrofolate reductase, interfering folic acid metabolism, selective inhibition of DNA, RNA and protein synthesis. For the cycle specific drugs, and alkylating agents without cross-resistance. Body subject to P-450 liver microsomal oxidase activity of a single after playing the cytotoxic effect of oral plasma Tmax of about 2 to 3 hours, plasma T1 / 2 to 13 hours, the main metabolite excreted through the urine. |
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Amitriptyline hydrochloride [549-18-8] |
This product is a tricyclic antidepressant, and its role is to inhibit the 5 - serotonin and norepinephrine reuptake, of 5 - HT reuptake inhibition stronger sedative and anticholinergic effects are also stronger. For the treatment of depression, anxiety, emotional stress, mental disorder. Gastrointestinal neurosis. |
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Amlodipine maleate [88150-47-4] |
This product is a calcium antagonist for the treatment of hypertension and angina. |
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Anastrozole [120511-73-1] |
As potent non-steroidal aromatase inhibitors. Can decrease plasma levels of estrogen, resulting in inhibition of mammary tumor growth. Clinic for postmenopausal women with advanced breast cancer treatment. |
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Aprepitant [170729-80-3] |
NK-1 receptor antagonist for reduction of postoperative vomiting |
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Armillarisin A [53696-74-5] |
For the treatment of acute biliary tract infection, and antibiotic efficacy slightly similar, but the treatment effect of obstruction were not significant. Also for the treatment of viral hepatitis. In addition, can also be used for the treatment of chronic gastritis. |
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Atorvastatin calcium [134523-03-8] |
Treatment of elevated total cholesterol, LDL cholesterol, elevated apolipoprotein B and triglycerides increased. Patients with primary hypercholesterolemia, including familial hypercholesterolemia (heterozygous type) or mixed hyperlipidemia (Fredrickson classification equivalent to the type Ⅱ a and Ⅱ b) patients |
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Azaperone [1649-18-9] |
This product is a relatively new class of antidepressant with anxiolytic properties of drugs now in clinical use of the Azar piperazine Long is buspirone, a partial 5-HT agonist effect. Buspirone for chronic anxiety, mixed anxiety and depression are effective, but exercise a certain delay. Common with other anti-anxiety drugs (eg: benzodiazepines) than any of Azar piperazine Lung virtually no cognitive side effects can be, and no significant withdrawal syndrome, therefore, the elderly buspirone person's anxiety drug treatment is particularly useful. |
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Azasetron hydrochloride [123040-69-7] |
Azasetron hydrochloride for the selection of 5-HT3 receptor antagonist, inhibited the anti-cancer drugs such as cisplatin induced nausea and vomiting. |
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Balofloxacin [127294-70-6] |
Gram-positive bacteria and gram-negative and anaerobic bacteria with broad-spectrum antimicrobial activity. Particularly MRSA, Streptococcus pneumoniae, Enterococcus faecalis and other Gram-positive bacteria activity than norfloxacin |
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Bambuterol hydrochloride [81732-46-9] |
Bronchial asthma, chronic asthmatic bronchitis, emphysema and other lung diseases associated with bronchospasm. |
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Benazepril hydrochloride [86541-74-4] |
Angiotensin converting enzyme inhibitors. Hydrolysis to form a strong beta activity that Pu Lila, blood angiotensin converting enzyme inhibition, angiotensin Ⅱ-mediated reduction of various effects. To reduce peripheral vascular resistance, lower blood pressure, but does not cause compensatory fluid retention, but also reduce ventricular afterload, heart rate, not faster. Improve left ventricular hypertrophy, diabetic glucose tolerance. |
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Bendazol [621-72-7] |
Smooth muscle inhibitors, with antihypertensive, antispasmodic, excited the role of the spinal cord, for use in vascular or other smooth muscle spasm, can be used for polio sequelae such as |
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Benidipine hydrochloride [91599-74-5] |
Is a dihydropyridine calcium antagonists, and the membrane potential-dependent calcium channel DHP binding site combined with inhibition of calcium influx, thereby dilating coronary and peripheral. For the treatment of hypertension and angina pectoris. |
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Besifloxacin [141388-76-3] |
For the treatment of bacterial conjunctivitis, is a new generation of fluoroquinolone antibiotics. |
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Betahistine dihydrochloride [5579-84-0] |
This product is double-monoamine oxidase inhibitor, on cerebral blood vessels, heart, particularly the vertebral artery in the expansion of the system have a more significant role in a significant increase in heart, brain and peripheral blood flow, improve blood circulation and reduce systemic blood pressure, In addition to increase before the end of the cochlea and the blood flow, thereby eliminating the inner ear, vertigo, tinnitus and ear a sense of closure, but also increased capillary permeability, promote the absorption of extracellular fluid, the elimination of lymphatic edema; to fight against catecholamine vasoconstriction and reduce arterial pressure, and plasma coagulation and inhibition of ADP induced platelet aggregation, thrombosis can extend the time for rats, as well as a slight diuretic effect.For the inner ear vertigo; of cerebral arteriosclerosis, ischemic cerebrovascular disease, head trauma or hypertension due to the erection of vertigo, tinnitus can also be used. |
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Biapenem [120410-24-4] |
A synthesis of carbapenem antibiotics; the salt white or almost white powder. Soluble in water, insoluble in common organic solvents. Dehydrogenation of renal peptidase Bimei Luo Peinan more stable, no combination of enzyme inhibitors. Against Gram-negative bacteria, especially against Pseudomonas aeruginosa stronger activity than imipenem; of aerobic gram-positive bacteria of antibacterial activity was slightly lower than imipenem; imipenem against anaerobic bacteria of the same activity . |
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Bisoprolol fumarate [104344-23-2] |
This product is β-blockers, bronchial and vascular smooth muscle of the β1-receptor with high affinity, so that the blood vessels to dilate, lowering blood pressure. For hypertension, coronary heart disease, and moderate to severe chronic stable heart failure embolism. |
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Blonanserin [132810-10-7] |
This product is a 5 - serotonin and dopamine antagonists (SDA), is the second-generation antipsychotics, haloperidol has the equivalent effect of dopamine D2 receptor antagonist, also has a strong 5-HT2A blocking effect , the selectivity of the two receptors more than the other antipsychotics. |
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Brinzolamide [138890-62-7] |
This product is sulfa drugs. Used to reduce elevated intraocular pressure following conditions: ocular hypertension, open angle glaucoma. Β-blockers may be as ineffective or are contraindicated in patients with disease treatment alone, or β-blockers as a collaborative treatment. |
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Buflomedil hydrochloride [35543-24-9] |
Buflomedil hydrochloride is a pharmacological effect with a variety of vasoactive drugs, chemicals known as 2 ', 4', 6'-trimethoxy -4-- (1 - pyrrolidinyl) benzene hydrochloride butyrylcholinesterase. Buflomedil for the inhibition of the major pharmacological effects of α adrenergic receptors, inhibit platelet aggregation, increased red blood cell deformability, non-specific calcium antagonism and enhanced oxygen utilization, thereby improving the nutritional blood flow in ischemic tissue. Cerebrovascular disease: brain vascular sclerosis, cerebral infarction, cerebral vascular accident recovery and sequelae, vascular dementia, vertigo. Peripheral vascular diseases, such as intermittent claudication, vasculitis. |
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Butenafine hydrochloride [101827-46-7] |
This product is benzylamine derivatives, and the mechanism for the selective inhibition of COX-fungal squalene, ergosterol interfere with fungal cell wall biosynthesis, lipid metabolism of fungi, so that fungal cell injury or death play the role of bactericidal and bacteriostatic. Mainly used by the floc rubrum, red rubrum, Trichophyton, and alopecia areata hair caused by dermatophytes such as toe ringworm, body ringworm, tinea corporis local treatment. |
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Butorphanol tartrate [58786-99-5] |
Butorphanol tartrate major metabolite of excited K-opioid receptor on U-receptor antagonist is a dual role with excitement and. It is mainly with the central nervous system (CNS) in the indirect interaction between these receptors play a role in its pharmacological effects, including analgesia. In addition to analgesic effects, CNS effects include reduction of the respiratory system of spontaneous breathing, coughing, vomiting and central nervous excitement, miotic, sedative and other pharmacological effects. |
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Calcium levofolinate [80433-71-2] |
In addition to the treatment of this product megaloblastic folic acid deficiency anemia, and cancer treatment used to increase folic acid antagonist (especially ammonia methotrexate, methotrexate and fluorouracil) antidote drug resistance (ie, ammonia tetrahydrofolate A rescue), but also for treatment of psoriasis and autoimmune diseases like rheumatoid arthritis drug, and chemical treatment used to improve for some antiparasitic drugs (for example, trimethoprim - sulfamethoxazole) resistance. Can be used in AIDS Pneumocystis carinii pneumonia in the adjuvant treatment of |
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Captopril [62571-86-2] |
For the synthetic angiotensin-converting enzyme (ACE) inhibitors, a major role in the renin - angiotensin - aldosterone system (RAA system). RAA system inhibition of angiotensin converting enzyme (ACE), to prevent or angiotensin converting angiotensin Ⅰ Ⅱ, and can inhibit aldosterone secretion, reduced Shuinazhuliu. For the treatment of various types of hypertension. |
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Carbachol [51-83-2] |
Can be generated directly on the miotic pupil sphincter function, as well as indirect effects of anti-cholinesterase, so miosis longer. Ophthalmic surgery in the anterior chamber injection of this product after 2 seconds, the pupil began to shrink, as fast powerful miotic. Angle closure glaucoma is disabled in the. Disabled persons in heart disease and bronchial asthma. |
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Carbazochrome sodium sulfonate [51460-26-5] |
This product can reduce the capillary permeability, promoting retraction of capillary fracture side effects, often resulting in increased capillary permeability in a variety of bleeding. For the urinary system, upper digestive tract, respiratory and gynecological and obstetrical diseases bleeding, can be used for trauma and surgical bleeding. |
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Carvedilol [72956-09-3] |
As α, β blockers, block the receptors in the role of both vasodilator for the treatment of mild and moderate hypertension or with renal dysfunction, diabetes, high blood pressure patients. |
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Chlormethine hydrochloride [55-86-7] |
Bifunctional alkylating agent nitrogen mustard as hydrochloric acid, the main inhibiting DNA synthesis, while RNA and protein synthesis is also inhibited. Its mechanism is nitrogen mustard 7th with guanine was covalently bound nitrogen to produce double-strand DNA cross-linking or DNA within the same chain of cross-linking of different bases, preventing DNA replication, causing cell damage or death. G1 phase of tumor cell killing effect and the M most of the large doses of both phases of the cell killing effect, is a cell cycle non-specific drugs. For malignant lymphoma, particularly Hodgkin's disease, endovascular treatment to control malignant pleural, pericardial and peritoneal effusions has a good effect. |
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Chlorzoxazone [95-25-0] |
This product is central muscle relaxant. It is mainly on the central nervous system, spine and brain cortex under the more sudden reflex arc suppression, and thus produces skeletal muscle spasms muscle relaxation to achieve analgesic effect. For a variety of acute and chronic soft tissue (muscle, ligament) sprain, contusion, muscle soreness after exercise, muscle spasm caused by central nervous system lesions and chronic fasciitis |
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Ciclopirox [29342-05-0] |
This product is broad-spectrum antifungal agents, mainly by changing the integrity of fungal cell membrane, causing an outflow of cells within the material, and block the uptake of precursor proteins, leading to fungal cell death, for dermatophytes, yeasts, and molds have strong inhibitory and bactericidal effect, strong permeability. Various actinomycetes, Gram-positive and gram-negative bacteria and mycoplasma, chlamydia, trichomoniasis, also have a certain inhibition. This product is white crystalline powder; odorless, bitter taste. The product in methanol, ethanol or chloroform soluble in dimethylformamide, or slightly soluble in water, slightly soluble in ether. |
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Cidofovir [113852-37-2] |
This product is a new open-loop nucleoside, potent selective antiviral drugs, in a dose-dependent inhibition of viral DNA synthesis. The product of intracellular enzymes into the cell after one or two phosphoric acid into derivatives, which products (especially in the second phosphate derivatives) can be more selective and potent inhibition of viral DNA synthesis. with a strong anti-herpes virus activity, especially on the effect of cytomegalovirus infection outstanding, are widely used in immunocompromised patients with cytomegalovirus HIV prevention and treatment. For CMV retinitis in AIDS patients. |
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Cilostazol [73963-72-1] |
Has a vasodilator effect and the role of anti-platelet function can be used to treat atherosclerosis, arteritis, thromboangiitis obliterans, diabetes due to chronic arterial occlusive disease. |
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Cisapride [81098-60-4] |
This product is the third generation of a new gastrointestinal prokinetic drug, its mechanism mainly through the intestinal muscular plexus release of acetylcholine and work, can significantly enhance gastric - duodenal digestion activity, coordinate and strengthen the gastric emptying to increase the small intestine, large intestine peristalsis and shorten the time of bowel movements, but does not affect gastric secretion. |
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Citalopram hydrobromide [59729-32-7] |
Is a strong, selective 5 - HT uptake inhibitor, has antidepressant effect. For depressive disorder. |
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Citicoline sodium [33818-15-4] |
Nerve activator. Citicoline build an important component of the biofilm, involved in the repair and regeneration, from the neuroprotective effect of acute stroke, post-surgical nerve injury caused by disturbance of consciousness, of Parkinson's syndrome, dementia, glaucoma and other obvious clinical effect. The appropriate treatment for brain diseases |
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Clodronic acid disodium salt [22560-50-5] |
This product is a bone metabolism regulator, can enter the bone matrix hydroxyapatite crystal, the crystal when the osteoclasts dissolve the drug is released, can inhibit osteoclast activity, and indirectly through osteoblasts play the role of inhibition of bone resorption. For concurrent malignant hypercalcemia; osteolytic metastasis caused by pain; can avoid or delay the metastatic bone cancer; various types of osteoporosis. |
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Clomipramine hydrochloride [17321-77-6] |
As tricyclic antidepressants, the main role is to block the central nervous system, norepinephrine and 5 - HT reuptake, of 5 - HT reuptake blocking stronger, and play the role of antidepressant and anxiolytic also sedative and anticholinergic effects. |
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Cloricromene [68206-94-0] |
This product is coronary vasodilators and antithrombotic drugs, which inhibit the attachment of leukocytes and endothelial cells in the vessel wall and increased polymorphonuclear leukocytes inhibit platelet aggregation. |
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Cyclosporin A [ 59865-13-3 |
This product is often associated with adrenal cortex hormones and other immunosuppressive agents in combination to enhance efficacy; for the prevention of allograft kidney, liver, heart, bone marrow and other organ or tissue transplant rejection occurred |
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Dacarbazine [4342-03-4 |
This product is an intermediate of purine biosynthesis, into the body by the liver microsomes to form a single methyl methyl compounds, has a direct cytotoxic effect. Major role in the G2 period. Inhibition of purine, RNA and protein synthesis, also affects DNA synthesis. So some people think is a alkylating agent. Clinic for malignant melanoma, about 20% to 30% effective, combined with vincristine and BCNU applications can improve the outcome. At this point, lung squamous cell carcinoma and undifferentiated carcinoma, leiomyosarcoma, fibrosarcoma and so have some therapeutic effect. |
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Decitabine [2353-33-5] |
This product is a DNA methyltransferase inhibitor, treatment of myelodysplastic syndrome with a clinical role. To the West after gemcitabine phosphorylation, directly on the DNA, inhibiting DNA methyltransferase, so that the low DNA methylation, cell differentiation death. For myelodysplastic syndrome. |
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Difenidol hydrochloride [3254-89-5] |
This product has a strong antiemetic effect and improve the anti-vertigo and nystagmus to antiemetic effects. |
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Dimesna [16208-51-8] |
Expectorants |
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Dirithromycin [62013-04-1] |
Macrolide antibiotics, as erythromycylamine prodrug, |
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Disodium pamidronate [109552-15-0] |
This product is double-phosphonic acid drugs, in vitro and animal studies indicate that hydroxyapatite could strongly inhibit the dissolution and the activity of osteoclasts on the bone uptake is significantly inhibited. Of metastatic bone cancer pain caused by pain, may be used to treat cancer-induced hypercalcemia. |
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Dithranol [1143-38-0] |
Anthralin major pharmacological effects including anti-epithelial cell proliferation and induce epithelial cell differentiation and anti-inflammatory effect. For psoriasis and other chronic skin diseases. |
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Docetaxel [114977-28-5] |
For early failure of chemotherapy in advanced or metastatic breast cancer treatment. Unless it is clinically contraindicated, the initial therapy should include anthracycline anti-cancer drugs. |
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Dofetilide [115256-11-6] |
Is a new class Ⅲ antiarrhythmic drugs can prolong the effective refractory period (ERP) and action potential duration (APD), clinically used for cardioversion of atrial fibrillation (Af) / atrial flutter (AF), the maintenance switch After the sinus rhythm recovery, reducing left ventricular dysfunction and myocardial infarction (MI) in patients after the danger of sudden death due to arrhythmia. |
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Domperidone maleate [99497-03-7] |
This product is a peripheral dopamine receptor antagonist, can promote the upper gastrointestinal tract motility and tension returned to normal, and promote gastric emptying, gastric and duodenal enhance movement, coordination of pyloric contraction, but also can enhance the motility of the esophagus and the lower esophageal sphincter tone. Because of its poor blood-brain barrier penetration, and almost no brain dopamine receptor antagonism, the spirit and therefore can be excluded from the central nervous system side effects. For the treatment of indigestion. |
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Donepezil hydrochloride [110119-84-1] |
Alzheimer's disease is a long-lasting (AD) in the symptomatic treatment drugs. Is the second generation of cholinesterase (ChE) inhibitors, the therapeutic effect is reversible inhibition of acetylcholinesterase (AchE) acid hydrolysis of acetylcholine induced increase in acetylcholine receptor site content. Donepezil may be other mechanisms, including the disposal of the peptide, neurotransmitter receptors or the direct effect of Ca2 + channels. |
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Doxazosin mesylate [77883-43-3] |
This product is long-acting α1-receptor blocker, to the surrounding blood vessels to dilate, reducing blood pressure, also can make the bladder, prostate smooth muscle relaxation, relieve urethral obstruction caused by benign prostatic hyperplasia symptoms. Clinic for hypertension, the treatment of benign prostatic hyperplasia. |
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